Private car service
Private car service treats the Overseas Highway as part of the product. The trip runs door to door from a Miami residence, hotel, MIA, or PortMiami to a Key West address, with vehicle class, a planned stop in Islamorada or Marathon, luggage count, and the return or wait-and-return plan settled in the quote before the trip starts. It is the option built for groups, gear, cruise timing, and travelers who cannot risk the return leg.
Shuttle or bus
Scheduled shuttles run Miami to Key West along US-1 with fixed stops through the Keys. They are the price-focused answer for solo travelers with light luggage, but the fixed schedule, shared cabin, and multi-stop routing make them a weak fit for families with gear, cruise connections, or anyone who needs a specific arrival time.
Flight to EYW
Key West International (EYW) is minutes from Old Town, and the airborne hop from Miami is short. The catch is everything around it: getting to MIA, security, boarding, baggage limits, and the transfer at EYW. For a Miami-origin trip, door-to-door time often lands closer to the drive than the flight schedule implies, and the Seven Mile Bridge stays out the airplane window.
Self-drive
Driving yourself keeps the scenery and the flexibility, but US-1 is a single corridor with long two-lane stretches, and Key West parking is constrained — hotels near Old Town charge for it and street parking is limited. Self-drive makes sense when the car earns its keep across several days of Keys exploring, not for a there-and-back transfer.
Rideshare
Rideshare can sometimes cover the southbound run if a driver accepts a 160-mile trip, but the return from Key West is the well-known problem: few long-distance drivers are positioned at the end of the Keys, so travelers report long waits or no matches at all. If the trip must include a reliable ride back, the honest answer is a pre-arranged round trip, not an app request from Duval Street.